Science

Molecular and Cellular Basis of Mi- Gene Mediated Host Resistance to Meloidogyne Species.

259 Hits Abdulaziz Issa Aug 19, 2022, 12:38 PM Oct 3, 2022, 2:17 PM

To sum up, the mechanisms mediated by Mi-resistance response to RKN infection are characterized by early hypersensitive response (HR), a highly strong and effective defense reaction in tomato (Solanumlycopersicum) and similar to the Me3 R gene in pepper (Capsicum annuum), in contrast to late necrosis of imperfect giant cells, as for the Me1 R gene of pepper and the Rk R gene of cowpea (Williamson, 1998, Pegard, et al., 2005, Das, et al., 2008). The Mi-1.2 NBS domain of the Mi-1.2 R protein can be autoactivated to trigger defense signaling in tomato (Tameling, et al., 2002, Lukasik-Shreepaathy, et al., 2012). The LRR domain of the Mi-1.2 protein has many roles in the regulation of RKN recognition and HR signaling (Hwang and Williamson, 2003). The chaperones Hsp90-1 and Sgt1 are involved in the formation of the Mi-1.2 signaling complex (Bhattarai, et al., 2007). The involvement of a mitogen-activated protein kinase (MAPK) cascade including LeMAPK1, LeMAPK2 and LeMAPK3 in Mi-1 resistance against potato aphids (Li, et al., 2006b). The Mi.1.2 R-proteins directly interfere with transcriptional regulators (SlWRKY72a and SlWRKY72b) to activate the transcriptional network controlling Mi-1.2-triggered ETI immunity.

Science

New superantibiotic capable of killing resistant bacteria

150 Hits Julio Contreras Aug 17, 2022, 3:57 PM Aug 17, 2022, 3:57 PM

A molecule capable of fighting more than 300 antibiotic-resistant bacteria is discovered and its efficacy has been demonstrated in laboratory...

Science

NASA’s Moon Rocket Heads Back to the Launchpad

2 Hits Francis Grace Aug 17, 2022, 5:38 AM Aug 17, 2022, 5:38 AM

The monster Space Launch System is starting off bright and early in front of its lunar excursion, which is booked...

Science

Outrageous material science of 'supercritical' matter might be shockingly straightforward

0 Hits Samsudeen Afeez Aug 16, 2022, 6:53 PM Aug 16, 2022, 6:53 PM

Outrageous material science of 'supercritical' matter might be shockingly straightforward